I-Dengue Virus IgM/IgG Antibody

Lo mkhiqizo ulungele ukutholwa kwekhwalithi yamasosha omzimba we-dengue virus, okuhlanganisa i-IgM ne-IgG, ku-serum yomuntu, i-plasma kanye namasampula egazi lonke.

I-Dengue fever yisifo esithathelwanayo esibangelwa igciwane lodenga, futhi futhi ingesinye sezifo ezithathelwanayo ezisakazwa kakhulu omiyane emhlabeni. Ngokwe-serologically, ihlukaniswe ngama-serotypes amane, i-DENV-1, i-DENV-2, i-DENV-3, ne-DENV-4^[1]. Igciwane lodenga lingabangela uchungechunge lwezimpawu zomtholampilo. Ngokomtholampilo, izimpawu eziyinhloko umkhuhlane omkhulu ongazelelwe, ukopha okukhulu, ubuhlungu obukhulu bemisipha nobuhlungu bamalunga, ukukhathala okukhulu, njll., futhi kuvame ukuhambisana nokuqubuka, i-lymphadenopathy kanye ne-leukopenia.^[2]. Ngokufudumala kwembulunga yonke okwandayo okwandayo, ukusatshalaliswa kwendawo komkhuhlane wodenga kuthanda ukusabalala, futhi izigameko nokuqina kwalo bhubhane nakho kuyanda. Umkhuhlane wodenga usuphenduke inkinga enkulu yezempilo yomphakathi emhlabeni jikelele.

Lo mkhiqizo uyikhithi esheshayo, esizeni futhi enembile yokuhlonza amasosha omzimba odenga (IgM/IgG). Uma ine-antibody ye-IgM, ibonisa ukutheleleka kwakamuva. Uma ine-antibody ye-IgG, ikhombisa isikhathi eside sokutheleleka noma ukutheleleka kwangaphambilini. Ezigulini ezinokutheleleka okuyinhloko, ama-antibodies e-IgM angatholakala ezinsukwini ezingu-3-5 ngemva kokuqala, futhi afinyelele phezulu ngemva kwamasonto angu-2, futhi angagcinwa izinyanga ezingu-2-3; Amasosha omzimba e-IgG angatholwa isonto eli-1 ngemuva kokuqala, futhi amasosha omzimba e-IgG angagcinwa iminyaka eminingana noma impilo yonke. Phakathi nesonto elingu-1, Uma ukutholwa kwezinga eliphezulu le-antibody ethile ye-IgG ku-serum yesiguli phakathi nesonto elilodwa kusukela ekuqaleni, kubonisa ukutheleleka kwesibili, futhi ukwahlulela okuphelele kungenziwa futhi kuhlanganiswe nesilinganiso se-antibody ye-IgM/IgG etholwe ngendlela yokuthwebula. Le ndlela ingasetshenziswa njengesengezo ezindleleni zokuthola i-viral nucleic acid.