Ukutholwa kwe-15-HPV MrNA IMRNA - Khomba ubukhona nomsebenzi we-HR-HPV

Umdlavuza wesibeletho, imbangela ehamba phambili yokufa kwabantu kwabesifazane emhlabeni wonke, kubangelwa ukutheleleka nge-HPV. Amandla we-Oncogenic wokutheleleka kwe-HR-HPV kuncike ekutheni izinkulumo ezikhuphukayo zezakhi zofuzo ze-E6 ne-E7. Amaprotheni e-E6 ne-E7 abopha amaprotheni esithi esithi smoree protesressor P53 ne-PRB ngokulandelana, futhi aqhube isimo sengcindezi yesibeletho kanye noguquko.

Kodwa-ke, ukuhlolwa kwe-HPV ye-DNA kuqinisekisa ubukhona begciwane, akuboni phakathi kwezifo zalemuva nangokubhala ngentshiseko. Ngokuphambene nalokho, ukutholwa kwe-HPV E6 / E7 Transcript kusebenza njenge-biomarker ekhethekile ye-acomal accogene nkulumo, futhi ngaleyo ndlela, ungumbikezeli onembile kakhudlwana we-cervical intraepithelial neoplasia (cin) noma i-carcinoma yokuhlasela.

I-HPV E6 / E7 MRNAUkuhlola kunikeza izinzuzo ezinkulu ekuvinjelweni komdlavuza wesibeletho:

• Ukuhlolwa kwengozi okunembile: Khomba ukutheleleka okusebenzayo, okunobungozi be-HPV, ukuhlinzeka ngokuhlolwa okunemba okuqondile kunokuhlolwa kwe-HPV DNA.
• I-Triage ephumelelayo: Abaqondisi be-Guides ekuboneni iziguli ezidinga uphenyo olunye, behlisa izinqubo ezingadingekile.
• Ithuluzi lokuhlola elingaba khona: lingasebenza njengethuluzi lokuhlola indawo yokufunda ngokuzayo, ikakhulukazi kubantu ababeka engcupheni enkulu.
• Izinhlobo eziyi-15 zengozi enkulu yabantu e-papillomavirus e6 / E7 gene gene dection Kit (Fleorescence PCC) kusuka ku- #mmt, ukuthola umaki ngokutheleleka okuqhubekayo kwe-HPVV, noma ukuphathwa kweziguli.

Izici zomkhiqizo:

• Ukuhlanganiswa okugcwele: Ama-15 we-HPV-HPV ahlobene nomdlavuza wesibeletho embozwe;
• Ukuzwela okuhle: amakhophi angama-500 / ml;
• Ukucaciswa Okuphakeme: Awukho umsebenzi wesiphambano noCytomegalovirus, i-HSV II neDNA yomuntu genomic;
• Okubizayo: Ukuhlola okuhlosiwe kuhlobene kakhulu nesifo esisebangelwe, ukunciphisa izivivinyo ezingadingekile ngezindleko ezengeziwe;
• Ukunemba okuhle kakhulu: IC yenqubo yonke;
• Ukuvumelana okubanzi: Ngezinhlelo ze-PCR ze-Mainstream;