Njalo ngonyaka ngo-Ephreli 17th usuku lomdlavuza womhlaba.
01 Izehlakalo zomdlavuza womhlaba
Eminyakeni yamuva nje, ngokwenyuka okuqhubekayo kwempilo yabantu nokucindezela kwengqondo, izehlakalo ze-tumors nazo ziyanda unyaka nonyaka.
Ama-Fumant Tumors (amakhansela) asephenduke ngenye yezinkinga ezinkulu zezempilo zomphakathi ezisongela impilo yabantu baseChina. Ngokusho kwemininingwane yakamuva yezibalo, ukufa kwama-tumus amabi abhajwe ama-23.91% azo zonke izimbangela zokufa phakathi kwabahlali, kanye nezigameko zokufa kabi ziye zaqhubeka nokuphakama kule minyaka eyishumi edlule. Kepha umdlavuza awusho "isigwebo sentambo." I-World Health Organisation iveze ngokusobala ukuthi inqobo nje uma itholwa kusenesikhathi, ama-60% -90% wamakhashane angalapheka! Ingxenye eyodwa kwezintathu yomdlavuza ingavinjelwa, ingxenye eyodwa kwezintathu yomdlavuza iyelapheka, futhi ingxenye eyodwa kwezintathu yomdlavuza ingalashwa ukuze kunwetshwe impilo.
02 Kuyini isimila
I-Tlamor ibhekisela kwinyoka entsha eyakhiwe ngokwakhiwa kwamaseli wezicubu zasendaweni ngaphansi kwesenzo sezinto ezahlukahlukene zezindlebe. Ucwaningo luthole ukuthi amaseli e-tumor athola izinguquko ze-metabolic ezahlukile kumaseli ajwayelekile. Ngasikhathi sinye, amaseli esithumbu angazivumelanisa nezinguquko endaweni ye-metabolic ngokushintsha phakathi kwe-glycolysis kanye ne-phosphorylation ye-oxidative.
03 Ukwelashwa komdlavuza ngamunye
Ukwelashwa komdlavuza okwenziwe ngazinye kususelwa kulwazi lokuxilongwa kwezifo zofuzo ezingeniswa izifo kanye nemiphumela yocwaningo olususelwa ebuhlotsheni. Inikeza isisekelo seziguli ukuthola uhlelo lokwelashwa olufanele, oluye lwaba umkhuba wokuthuthuka kokwelashwa kwanamuhla. Ucwaningo lweMitholampilo lukuqinisekisile lokho ngokuthola ukuguqulwa kwezakhi zofuzo ze-biomaskers, uhlobo lwe-gene snp ukuthayipha kwezidakamizwa zezinto eziphilayo ukubikezela ukusebenza kwezidakamizwa futhi kuhlole ukwelashwa okukodwa, kungathuthukisa ukusebenza kahle ukusabela, ukukhuthaza ukusetshenziswa okunengqondo kwezinsiza zezokwelapha.
Ukuhlolwa kwama-molecular komdlavuza kungahlukaniswa ngezinhlobo ezi-3 eziphambili: Ukuxilonga, ifa, nezokwelapha. Ukuhlolwa kwezokwelapha kusemqoka we- "Therapeutic Pathology" noma umuthi owenziwe ngezifiso, kanye namasosha omzimba amaningi kanye nama-molecule ama-molecule inunitors angafakwa ekwelapheni ama-tumors.
Ukwelashwa okuhlosiwe kwamangqamuzana kwama-tumors kuhlose ama-molecule okumaka ama-molecule amaseli we-tumor futhi angenelele kwinqubo yamaseli anomdlavuza. Umphumela wayo ikakhulukazi kumaseli we-tumor, kepha awunamthelela omncane kumaseli ajwayelekile. Ama-tumor agrem factor recectors, ama-molecule wokudlulisela iziginali, amaprotheni omjikelezo weseli, abalawuli be-apoptoolic, inzbertic enzyme, njll. NgoDisemba 28, 2020, "izindlela zokuphatha zokwelashwa kwemitholampilo yezidakamizwa ezi-Antineoplastic (icala)" ezikhishwe ngokusobala ukuthi izidakamizwa ezihlosiwe, umgomo wokuzisebenzisa kufanele alandelwe ngemuva ukuhlolwa kwe-gene okuqondisiwe.
04 Ukuhlolwa kwezakhi zofuzo okubhekiswe kwigciwane
Kunezinhlobo eziningi zokuguqulwa kwezakhi zofuzo kuma-tumors, kanye nezinhlobo ezahlukene zokuguqulwa kwezakhi zofuzo zisebenzisa izidakamizwa ezihlukile ezihlosiwe. Kuphela ngokucacisa uhlobo lokuguqulwa kwezakhi zofuzo nokukhetha kahle ukwelashwa kwezidakamizwa okuhlosiwe kungazuzisa iziguli. Izindlela zokutholwa kwama-molecular zazisetshenziselwa ukuthola ukuhlukahluka kofuzo okuhlobene nezidakamizwa ezibhekiswe ezihlaselwayo ezihlosiwe. Ngokuhlaziya umthelela wokuhlukahluka kofuzo ngokusebenza kwezidakamizwa, singasiza odokotela ukuthi bathuthukise uhlelo olufanele ukwelashwa komuntu ngamunye
Isixazululo se-05
IMacro & Micro-Test ithuthukise uchungechunge lwamakhithi wokutholwa kokutholwa kwe-tumor gene, ukuhlinzeka ngesisombululo sonke se-tubiture okuhlosiwe.
I-Human Egfr gene 29 Ikhithi yokuthola izinguquko (Fleorescence PCR)
Le khithi isetshenziselwa ukutholwa kwe-vitro ngokufanelekile kwezinguquko ezijwayelekile kuma-exths 18-21 wefuzo le-EGFR ngamasampula avela ezigulini ezinomdlavuza we-Human angewona ama-Lung.
1. Uhlelo lwethula isithenjwa sekhwalithi yangaphakathi, esingabheka kahle inqubo yokuhlola futhi siqinisekise ikhwalithi yokuhlolwa.
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3. Ukucaciswa okuphezulu: Akukho ukusabela okuwela nge-DNA yohlobo lwabantu yasendle kanye nezinye izinhlobo eziguqukayo.
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I-Kras 8 Detenion Detection Kit (Fleorescence PCR)
Le khithi yenzelwe ukutholwa kwe-vitro okufanelekile kokuguqulwa kwezimali okungu-8 kumakhodi ayi-12 no-13 we-K-RAS Gene kwi-DNA ekhishwe ku-Parraffer-Eshunyelwe.
1. Uhlelo lwethula isithenjwa sekhwalithi yangaphakathi, esingabheka kahle inqubo yokuhlola futhi siqinisekise ikhwalithi yokuhlolwa.
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3. Ukucaciswa okuphezulu: Akukho ukusabela okuwela nge-DNA yohlobo lwabantu yasendle kanye nezinye izinhlobo eziguqukayo.
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I-Human Eml4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Le khithi isetshenziselwa ukuthola kahle izinhlobo eziyi-12 zokuguqulwa kwe-EML4-ALK Fusion Gene kumasampula eziguli zomdlavuza we-Human Nonsmall Cell Lung eVitro.
1. Uhlelo lwethula isithenjwa sekhwalithi yangaphakathi, esingabheka kahle inqubo yokuhlola futhi siqinisekise ikhwalithi yokuhlolwa.
2. Ukuzwela okuphezulu: Le khithi ingabona izinguquko eziguqukayo njengamakhophi angama-20.
3. Ukucaciswa okuphezulu: Akukho ukusabela okuwela nge-DNA yohlobo lwabantu yasendle kanye nezinye izinhlobo eziguqukayo.
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I-Human ROS1 Fusion Gene Mutation Detection Dection Kit (Fluorescence PCR)
Le khithi isetshenziselwa ukutholwa kokufaneleka kwe-vitro yezinhlobo eziyi-14 ze-gebheli tene gene izinguquko kumasampula omdlavuza we-Human amancane amancane.
1. Uhlelo lwethula isithenjwa sekhwalithi yangaphakathi, esingabheka kahle inqubo yokuhlola futhi siqinisekise ikhwalithi yokuhlolwa.
2. Ukuzwela okuphezulu: Le khithi ingabona izinguquko eziguqukayo njengamakhophi angama-20.
3. Ukucaciswa okuphezulu: Akukho ukusabela okuwela nge-DNA yohlobo lwabantu yasendle kanye nezinye izinhlobo eziguqukayo.
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I-Human Braf gene v600e dection sokutholwa kwe-Mutation (Fleorescence PCR)
Le kit yokuhlola isetshenziselwa ukuthola kahle i-braf gene gene gene v600ation kumaparafini ashunyekwe amapharafini we-melanoma yabantu, umdlavuza we-colorectal, umdlavuza we-thyroid nomdlavuza wamaphaphu eVitro.
1. Uhlelo lwethula isithenjwa sekhwalithi yangaphakathi, esingabheka kahle inqubo yokuhlola futhi siqinisekise ikhwalithi yokuhlolwa.
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3. Ukucaciswa okuphezulu: Akukho ukusabela okuwela nge-DNA yohlobo lwabantu yasendle kanye nezinye izinhlobo eziguqukayo.
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| Inombolo yekhathalogi | Igama lomkhiqizo | Ukucacisa |
| I-HWTS-TM012A / B | I-Human Egfr Gene 29 I-Mutations Detection Kit (Fluorescence PCR) | Izivivinyo eziyi-16 / kit, izivivinyo ezingama-32 / kit |
| I-HWTS-TM014A / B | I-Kras 8 Detenion Detection Kit (Fleorescence PCR) | Izivivinyo ezingama-24 / kit, izivivinyo ezingama-48 / kit |
| Hwts-tm006a / b | I-Human Eml4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | Izivivinyo ezingama-20 / kit, izivivinyo ezingama-50 / kit |
| Hwts-tm009a / b | I-Human ROS1 Fusion Gene Mutation Detection Dection Kit (Fluorescence PCR) | Izivivinyo ezingama-20 / kit, izivivinyo ezingama-50 / kit |
| Hwts-tm007a / b | I-Human Braf gene v600e dection sokutholwa kwe-Mutation (Fleorescence PCR) | Izivivinyo ezingama-24 / kit, izivivinyo ezingama-48 / kit |
| Hwts-ge010a | I-Human Bcr-Abl Fusion Gene Mutation Dection Dection Dection (Fluorescence PCR) | Izivivinyo ezingama-24 / kit |
Isikhathi Sokuthumela: APR-17-2023