Ukuhlolwa kwe-HPV genityping njenge-biomarkers yokuxilonga yengozi yomdlavuza wesibeletho - ekusetshenzisweni kokutholwa kwe-genotyping ye-HPV

Ukutheleleka kwe-HPV kwenzeka njalo kubantu abakhuthazayo ngokocansi, kepha ukutheleleka okuphikelelayo kukhula kuphela ngengxenye encane yamacala. Ukuphikelela kwe-HPV kufaka phakathi ingozi yokuthuthukisa izilonda zesibeletho ezinokulunga futhi, ekugcineni, umdlavuza womlomo wesibeletho

Ama-HPV awakwazi ukubalwaeVitroNgezindlela ezijwayelekile, kanye nokuhlukahluka okungokwemvelo kwendlela yokuzivikela komzimba ngemuva kokutheleleka kulimaza ukusetshenziswa kokuhlolwa kwe-antibod ekhethekile ye-HPV ekuxilongeni. Ukuxilongwa kokutheleleka kwe-HPV kungukuthi, ngakho-ke, kutholakala ukuhlolwa kwamangqamuzana, ikakhulukazi ngokutholwa kwe-genomic HPV DNA.

Njengamanje, izindlela ezahlukahlukene zezentengiselwano ze-HPV genetyping zikhona. Ukukhetha okulungile kuncike ekusetshenzisweni okuhlosiwe, okungukuthi: Ukuhlolwa kwe-Epidemiology, Ukuhlolwa Komugqwala, noma Izifundo Zomtholampilo.

Okwezifundo ze-Eshremeniological, izindlela ze-HPV genityping zivumela ukudweba kohlobo oluthile.
Ukuhlolwa kokugoma, lezi zindlela zokuqinisekisa imininingwane maqondana nezinguquko ekwandeni kwezinhlobo ze-HPV ezingafakwanga emijovo yokugoma yamanje, futhi kube lula ukulandela izifo eziphikelelayo
Kwezifundo zemitholampilo, imihlahlandlela yamanje yamazwe omhlaba itusa ukusetshenziswa kwezivivinyo ze-HPV ze-genotyping phakathi kwabesifazane iminyaka engama-30 nangaphezulu nge-cytolology engemihle kanye nemiphumela emihle ye-HPV-16 ne-HPV-18. Ukuthola i-HPV nokubandlulula ama-genotypes aphezulu futhi aphansi futhi ngaphezulu ukuthola iziguli ngezifo ezifanayo ze-genotype eziphikelelayo, okuholela ekuphathweni okungcono kwemitholampilo.

I-Macro & Micro-Test HPV Genityping Kits:

• Izinhlobo eziyi-14 ze-HPV (i-genotyping) ikhithi yokutholwa kwe-nucleic acid (i-fluorescence PCR)
• Izinhlobo ze-Freeze-ezomiswa eziyi-14 (i-genotyping) i-nucleic acid detection kit (i-fluorescence PCR)
• Izinhlobo ezingama-28 HPV (Geniotyping) Ukutholwa Kit (Fluorescence PCC) (18 HPSVS +10 LR-HPVS)
• I-Freeze-yomisiwe Izinhlobo ezingama-28 ze-HPV (Geniotyping) Kit (Fluorescence PCR)

Izici zomkhiqizo ezibalulekile:

• Ukutholwa kanyekanye kwama-genotypes amaningi ekuphenduleni okukodwa;
• Isikhathi esifushane se-PCR sokuguqula izinqumo ezisheshayo zemitholampilo;
• Izinhlobo eziningi zesampula (umchamo / swab) ukuze uthole ukuhlolwa ukutheleleka kokutheleleka kwe-HPV okuthe xaxa;
• Izilawuli zangaphakathi ezimbili zivimbela ama-positives angamanga futhi aqinisekise ukuthembeka kokuhlola;
• Izinguqulo eziwuketshezi nezilolophilisiwe zezinketho zamakhasimende;
• Ukuhambisana nezinhlelo eziningi ze-PCR zokuguqulwa okwengeziwe kwelebhu.