Usongo Lomhlaba Wonke Luyashesha
Umbiko omusha we-World Health Organisation (WHO), i-Global Antibiotic Resistance Surveillance Report 2025, unikeza isixwayiso esiqinile: ukwanda kokumelana namagciwane (i-AMR) kudlula ikhono lethu lokulwa nakho. Phakathi kuka-2018 no-2023, ukumelana kwanda ngaphezu kuka-2023.40%ukuqapha inhlanganisela ye-pathogen-antibiotic, kanye nokwanda okumaphakathi konyaka kwe-5-15%.
Umthwalo awuhlanganyelwa ngokulinganayo. Umbiko ulinganisela ukuthi ukumelana nama-antibiotic kuphezulu kakhulu e-WHO South-East Asia naseMpumalanga Mediterranean Regions, lapho inani elikhulu khona1 kwabangu-3Ukutheleleka okubikiwe bekungamelani. Le nkinga ekhulayo isongela ukwehlisa amandla ezokwelapha zesimanje, okwenza ukutheleleka okuvamile kuphinde kube yingozi empilweni futhi kubeke engcupheni impumelelo yokuhlinzwa, ukwelashwa ngamakhemikhali, kanye nezinye izinqubo ezibalulekile.
Igebe Lokuxilonga Empini Ye-AMR
UMqondisi-Jikelele we-WHO, uDkt. Tedros Adhanom Ghebreyesus, ugcizelele ukuthi ukulwa ne-AMR kudinga ukuqinisa ukuqapha nokuqinisekisa ukufinyelela emithini efanele kanye nokuxilonga. Inkinga ebalulekile kule mpi isikhathi esithathayo ukuhlonza ngokunembile amagciwane amelana nezifo. Izindlela zendabuko zingathatha izinsuku, ziphoqe odokotela ukuthi banikeze ama-antibiotic e-broad spectrum ngokwesayensi—umkhuba okhuthaza umjikelezo wokumelana nezifo.
Yilapho ukuxilongwa okuseqophelweni eliphezulu kulungele ukushintsha umdlalo. Ngokunikeza ukuhlonza okusheshayo nokunembile kwezindlela zokumelana, kunikeza abahlinzeki bezempilo amandla okwenza izinqumo ezinolwazi nezisindisa impilo ngokushesha.
Ukuhlolwa Okukhulu Nokuncane's Izixazululo: Ukuxilongwa Okunembile Kokulwa Nenkinga Ye-AMR
Ukuphendula ngqo izinselele ezichazwe yi-WHO, sinikeza izixazululo ezimbili zokuxilonga ezihlanganisiwe ezenzelwe ukuletha isivinini, ukunemba, kanye nokuguquguquka okudingekayo ukuvikela iziguli nokuvikela izinhlelo zokunakekelwa kwempilo.
Isixazululo 1: Kuqinisekiswe yi-CEOkusheshayoIkhithi Yokuthola I-Carbapenemase
-Isivinini Nokunemba Okungalingani:Le khithi engenazo izinsimbi ezintsha ithola izakhi zofuzo ezinhlanu ezibalulekile ze-carbapenemase (i-KPC, i-NDM, i-OXA-48, i-VIM, i-IMP)—ezihlanganisa okungaphezulu kwama-95% ezinhlobo zezokwelapha ezaziwayo—ngesikhathi njeimizuzu eyi-15Njengoba inozwela olungaphezulu kuka-95%, inikeza imiphumela ethembeke kakhulu lapho kudingeka, iguqula isikhathi sokulinda sibe yisikhathi sesenzo esiwujuqu.
-Iziqondiso Ukwelashwa Okuqondiwe Ngokushesha:Le khithi iguqula ukuphathwa kwezokwelapha ngokuletha idatha esebenzayo ngokushesha. Lokhu kwenza odokotela bakwazi ukuqala ukwelashwa ngama-antibiotic okusebenza kahle kakhulu ngokushesha, okuthuthukisa kakhulu imiphumela yeziguli ezisengozini enkulu e-ICU, e-oncology, kanye nasemagumbini okuhlinzwa.
-Kuvikela Izinhlelo Zokunakekelwa Kwezempilo:Isebenza njengethuluzi elibalulekile lokulawula ukutheleleka kanye nezinhlelo zokuphatha amagciwane. Ukushesha kwayo kubalulekile ekuvimbeleni ukuqubuka kwezifo ezindaweni ezinobungozi obukhulu, kusiza ekunciphiseni ukuhlala esibhedlela kanye nezindleko ezihlobene nakho, ngaleyo ndlela kuvikelwe izinsiza zezikhungo.
Isixazululo 2: Amandla Ahlanganisiwe e-AIO800 +Ama-moleculeIkhithi ye-CRE
I-Molecular POCT eyisampula yokuphendula inikeza ikhambi eliphelele nelinembile.
-Ukutholwa Okuphelele Kwe-Multiplex:Lesi sixazululo sikhombaizakhi zofuzo eziyisithupha ezinkulu ze-carbapenemase (i-KPC, i-NDM, i-OXA-48, i-OXA-23, i-VIM, i-IMP)ngokuhlolwa okukodwa. Lokhu kufinyelelwa okubanzi kwenza kube lula ukuhamba komsebenzi, kunciphisa isidingo sokuhlolwa okuningi, futhi kunciphisa kakhulu izindleko zokuxilonga.
- Ukuzwela Okuphezulu Nokucacile:Yakhelwe ukunemba okumangalisayo, ikhithi ithola okungenani1,000 CFU/mLngaphandle kokusabela okuxubile, okuqinisekisa ukuxilongwa okuthembekile ngisho nasezibonelweni eziyinkimbinkimbi, ezinama-polymicrobial.
-Ukuguquguquka Okuphezulu Kwepulatifomu:Idizayinelwe ukusetshenziswa kabanzi, ikhithi iyahambisana kokubili ne-othomathikhi egcwele, ne-high-throughputUhlelo lwe-AIO800kanye nezinsimbi ze-PCR ezivamile.
Uhlelo lwe-AIO800 luchaza kabusha ukusebenza kahle ngomklamo walo ohlanganiswe ngokuphelele, lunikeza imiphumela emizuzwini engu-76 kuphela ngenkathi lufaka uhlelo lokuphepha olunezingqimba ezingu-11 ukuze kuncishiswe izingozi zokungcola.
Ukuguqula Igagasi Ngokuhlakanipha Okufike Ngesikhathi
Idatha yakamuva ye-WHO ikwenza kucace ukuthi i-AMR ayilona usongo lwesikhathi esizayo kodwa ingozi yamanje nekhulayo. Indlela eya phambili idinga indlela enezici eziningi lapho ukuxilongwa okuthuthukisiwe kudlala indima ebalulekile. Izixazululo zethu zinikeza "ubuhlakani obufika ngesikhathi" obudingekayo ukuze kuhlale kuphambi kwamagciwane amelana namagciwane, kuvumela ukwelashwa okuqondiwe, kulawulwe ukuqubuka, futhi kugcinwe amazinga okuphatha ama-antibiotic emhlabeni jikelele.
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Isikhathi sokuthunyelwe: Jan-19-2026