Qaphela ukuhlolwa kwe-GBS kusenesikhathi

01 Kuyini i-GBS?

I-Group B Streptococcus (GBS) iyi-streptococcus ene-Gram-positive ehlala emgudwini wokugaya ukudla ophansi kanye ne-genitourinary tract yomzimba womuntu. Iyi-pathogen enobungozi. I-GBS ithinta kakhulu isibeletho kanye nolwelwesi lomntwana ngesitho sangasese sowesifazane esikhuphukayo. I-GBS ingabangela ukutheleleka komgudu womchamo kamama, ukutheleleka ngaphakathi kwesibeletho, i-bacteremia kanye ne-postpartum endometritis, futhi yandise ingozi yokubeletha ngaphambi kwesikhathi noma ukuzalwa komntwana eshonile.

I-GBS ingaholela nasekuthelelekeni kwezinsana noma kwezinsana. Cishe u-10%-30% wabesifazane abakhulelwe bahlushwa ukutheleleka kwe-GBS. U-50% walokhu ungadluliselwa ngqo kosana olusanda kuzalwa ngesikhathi sokubeletha ngaphandle kokungenelela, okuholela ekuthelelekeni kwezinsana.

Ngokwesikhathi sokuqala kokutheleleka kwe-GBS, kungahlukaniswa izinhlobo ezimbili, eyodwa yi-GBS early-onset disease (GBS-EOD), eyenzeka ezinsukwini eziyi-7 ngemva kokubeletha, ikakhulukazi eyenzeka emahoreni ayi-12-48 ngemva kokubeletha, futhi ikakhulukazi ibonakaliswa njenge-bacteremia yezingane ezisanda kuzalwa, i-pneumonia, noma i-meningitis. Enye yi-GBS sekwephuzile-onset disease (GBS-LOD), eyenzeka kusukela ezinsukwini eziyi-7 kuya ezinyangeni ezi-3 ngemva kokubeletha futhi ikakhulukazi ibonakaliswa njenge-bacteremia yezingane ezisanda kuzalwa/izinsana, i-meningitis, i-pneumonia, noma ukutheleleka kwezitho zomzimba nezithambile.

Ukuhlolwa kwe-GBS ngaphambi kokubeletha kanye nokungenelela kwama-antibiotic ngaphakathi kokubeletha kunganciphisa ngempumelelo inani lokutheleleka kwezingane ezisanda kuzalwa, kwandise izinga lokusinda kwezingane ezisanda kuzalwa kanye nekhwalithi yokuphila.

02 Ungakuvimbela kanjani?

Ngo-2010, i-US Centers for Disease Control and Prevention (CDC) yasungula "Iziqondiso Zokuvimbela i-GBS Yokubeletha", yancoma ukuhlolwa okuvamile kwe-GBS emavikini angu-35-37 okukhulelwa ku-trimester yesithathu.

Ngo-2020, i-American College of Obstetricians and Gynecologists (ACOG) "Consensus on the Prevention of Early-onset Group B Streptococcal Disease in Newborn" incoma ukuthi bonke abesifazane abakhulelwe kufanele bahlolwe i-GBS phakathi kwamasonto angu-36+0-37+6 okukhulelwa.

Ngo-2021, i-"Expert Consensus on the Prevention of Perinatal Group B Streptococcal Disease (China)" eyakhishwa yi-Perinatal Medicine Branch ye-Chinese Medical Association incoma ukuhlolwa kwe-GBS kubo bonke abesifazane abakhulelwe emavikini angu-35-37 okukhulelwa. Incoma ukuthi ukuhlolwa kwe-GBS kusebenze amasonto ama-5. Futhi uma umuntu ongenayo i-GBS engakabelethi isikhathi esingaphezu kwamasonto ama-5, kunconywa ukuthi kuphindwe ukuhlolwa.

Isixazululo se-03

I-Macro & Micro-Test isungule i-Group B Streptococcus Nucleic Acid Detection Kit (Fluorescence PCR), ethola amasampula afana nomgudu wokuzala womuntu kanye nokuphuma kwe-rectal ukuhlola isimo sokutheleleka kwe-streptococcal kwe-group B, futhi isize abesifazane abakhulelwe ngokuxilongwa kokutheleleka kwe-GBS. Lo mkhiqizo uqinisekiswe yi-EU CE kanye ne-US FDA, futhi usebenza kahle kakhulu ngomkhiqizo kanye nesipiliyoni esihle somsebenzisi.

Izinzuzo

Okusheshayo: Ukusampula okulula, ukukhipha isinyathelo esisodwa, ukutholwa okusheshayo

Ukuzwela okuphezulu: i-LoD yekhithi ingamakhophi ayi-1000/mL

Izinhlobo eziningi: kufaka phakathi izinhlobo ezingu-12 ezifana ne-la, lb, lc, II, III

Ukulwa nokungcola: I-enzyme ye-UNG yengezwa ohlelweni ukuze kuvinjelwe ngempumelelo ukungcola kwe-nucleic acid elabhorethri

 

Inombolo Yekhathalogi	Igama Lomkhiqizo	Imininingwane
I-HWTS-UR027A	Ikhithi Yokuthola I-Streptococcus Nucleic Acid Yeqembu B (i-Fluorescence PCR)	Ukuhlolwa okungu-50/ikhithi
I-HWTS-UR028A/B	Ikhithi Yokuthola I-Streptococcus Nucleic Acid Yomisiwe Ngeqhwa Yeqembu B (i-Fluorescence PCR)	Ukuhlolwa okungu-20/ikhithiUkuhlolwa okungu-50/ikhithi