Isikhunta Esivamile, Imbangela Eyinhloko Ye-Vaginitis kanye Nezifo Zokhunta Zamaphaphu - Candida Albicans

Ukubaluleka Kokutholwa

I-fungal candidiasis (eyaziwa nangokuthi ukutheleleka kwe-candidal) ivame kakhulu. Kunezinhlobo eziningi ze-Candida futhiizinhlobo ezingaphezu kuka-200 ze-Candida kadekutholwe kuze kube manje.Candida albicans (CA) yiyona pathogenic kakhulu, okulandisayo cishe amaphesenti angama-70 azo zonke izifo zomtholampilo.I-CA, eyaziwa nangokuthi i-Candida emhlophe, imvamisa yenza i-parasitize kulwelwesi lwamafinyila esikhumbeni somuntu, umgodi womlomo, umgudu wamathumbu, isitho sangasese sowesifazane, njll.A kungenzeka kubangela ukutheleleka kwesistimu, ukutheleleka kwesitho sangasese sowesifazane, ukutheleleka komgudu wokuphefumula ophansi, njll.

I-Vaginitis:Cishe u-75% wabesifazane uba ne-vulvovaginal candidiasis (VVC) okungenani kanye empilweni yabo, futhi ingxenye yabo izophinde ivele. Ngaphezu kwezimpawu ezibuhlungu zomzimba ezinjengokulunywa nokushiswa kwe-vulvovaginal, izimo ezinzima zingase zibangele ukungahlaliseki, okusobala kakhulu ebusuku, futhi kuthinta kakhulu imizwelo nokusebenza kwengqondo yesiguli. I-VVC ayinakho ukubonakaliswa okuqondile komtholampilo, futhi ukuhlolwa kwaselabhorethri kuyisihluthulelo sokuxilongwa.

Ukutheleleka kwe-Pulmonary fungal:CA ukutheleleka kuyimbangela ebalulekile yokufa ngenxa yokutheleleka esibhedlela futhi ibalelwa ku-40% aIziguli ezigula kakhulu e-ICU. Ucwaningo lwe-multicenter retrospective lwesifo se-pulmonary fungal e-China kusukela ngo-1998 kuya ku-2007 lwathola ukuthi i-candidiasis yamaphaphu ibalelwa ku-34.2%, okuyi-34.2% yayo.CA I-65% ye-candidiasis yamaphaphu. Indawo yokuphefumula CA ukutheleleka akunazo izimpawu zomtholampilo ezijwayelekile futhi kunokucaciswa okuphansi kokubonakaliswa kwezithombe, okwenza ukuxilonga kusenesikhathi kube nzima. Ukuvumelana kochwepheshe ekuxilongweni nasekulashweni kwesifo sokukhunta kwamaphaphu kuncoma ukusetshenziswa kwamasampula esikhwehlela akhwehlela ajule, aqinise ukuhlolwa kwebhayoloji yamangqamuzana, kanye nokuhlinzeka ngezinhlelo ezihambisanayo zokwelashwa kwesikhunta.

Izinhlobo Zesampula

 

Isixazululo Sokuthola

Izici zomkhiqizo

Ukusebenza kahle:I-Isothermal amplification yokwenza lula ukukhulisa ngomphumela phakathi kwemizuzu engama-30;

Ukucaciswa okuphezulu: Si-pecific primer kanye ne-probe (rProbe)yakhelweezifundeni ezigcinwe kakhulu ze-CAngesistimu evalwe ngokugcwele ukuze kutholwe ngokuqondile i-CA DNA kuma-specimens.Ayikho i-cross-reactivity namanye amagciwane okutheleleka kwe-urogenital tract;

Ukuzwela okuphezulu: I-LoD ye-10² amagciwane/mL;

I-QC esebenzayo: Ireferensi yangaphakathi yangaphandle yokulawula i-reagent kanye nekhwalithi yokusebenza nokugwema okungalungile okungamanga;

Imiphumela enembile: izehlakalo eziyi-1,000 zamasenti amaningir ukuhlolwa komtholampilo nge-ainani lokuthobela ngokupheleleof 99.7%;

Ukumbozwa okubanzi kwama-serotypes: Wonke ama-serotypes e-Candida albicans A, B, Cehlanganisiwe ngeimiphumela engaguqukiuma kuqhathaniswa neukulandelana kokutholwa;

Ama-reagents avuliwe: Ihambisana ne-PCR evamile yamanjesystems.

Ulwazi Lomkhiqizo

Ikhodi Yomkhiqizo	Igama Lomkhiqizo	Ukucaciswa	Inombolo yesitifiketi.
I-HWTS-FG005	I-Nucleic Acid Detection Kit esekelwe ku-Enzymatic Probe Isothermal Amplification (EPIA) ye-Candida Albicans	50 izivivinyo/ikhithi
I-HWTS-EQ008	Easy AmpIsistimu Yokuthola I-Fluorescence Isothermal yesikhathi sangempela	I-HWTS-1600P 4 iziteshi ze-fluorescence	I-NMPA2023322059
I-HWTS-EQ009		I-HWTS-1600s 2iziteshi ze-fluorescence