Ukutholwa Kwesifo Sofuba Ngesikhathi Esifanayo Nokumelana Ne-RIF kanye ne-NIH

Isifo Sofuba (TB), esibangelwa isifo sofuba iMycobacterium, sisalokhu siwusongo empilweni yomhlaba wonke. Futhi ukwanda kokumelana nemithi ebalulekile yesifo sofuba njengeRifampicin (RIF) kanye ne-Isoniazid (INH) kuyisithiyo esibalulekile futhi esikhulayo emizamweni yokulawula isifo sofuba emhlabeni wonke. Ukuhlolwa okusheshayo nokunembile kwe-TB kanye nokumelana ne-RIF kanye ne-INH kunconywa yi-WHO ukuze kutholakale iziguli ezithelelekile ngesikhathi futhi zinikezwe ukwelashwa okufanele ngesikhathi esifanele.

Izinselele

Kulinganiselwa ukuthi abantu abayizigidi ezingu-10.6 bagula nge-TB ngo-2021, okukhuphuke ngo-4.5% kusuka ku-10.1 million ngo-2020, okwaholela ekufeni okulinganiselwa ku-1.3 million, okulingana namacala angu-133 kubantu abayi-100,000.

I-TB engazweli emithini, ikakhulukazi i-MDR-TB (engazweli ku-RIF kanye ne-INH), ithinta kakhulu ukwelashwa kanye nokuvinjelwa kwe-TB emhlabeni jikelele.

Ukuxilongwa okusheshayo ngesikhathi esisodwa kwe-TB kanye ne-RIF/INH ukumelana kuyadingeka ngokushesha ukuze kutholakale ukwelashwa kwangaphambi kwesikhathi futhi okuphumelelayo uma kuqhathaniswa nemiphumela yokuhlolwa kokuzwela kwemithi eyephuzile.

Isixazululo Sethu

Ukutholwa kwe-TB okungu-3-in-1 kukaMarco & Micro-Test kokutheleleka kwe-TB/RIF kanye nokutholwa kokumelana ne-NIH Kitkwenza kube lula ukuthola i-TB kanye ne-RIF/INH ngendlela ephumelelayo ekutholakaleni okukodwa.

Ubuchwepheshe bokuncibilikisa i-Melting curve bubona ngesikhathi esisodwa i-TB kanye ne-MDR-TB.

Ukutholwa kwe-TB/MDR-TB okungu-3-in-1 okunquma ukutheleleka kwe-TB kanye nokumelana nomuthi wokuqala oyinhloko (i-RIF/INH) kwenza ukwelashwa kwe-TB kube ngesikhathi nangokunembile.

I-Mycobacterium Tuberculosis Nucleic Acid kanye ne-Rifampicin, Ikhithi Yokuthola Ukumelana ne-Isoniazid (I-Melting Curve)

Uphumelela ekuhlolweni kwe-TB okuphindwe kathathu (ukutheleleka kwe-TB, ukumelana ne-RIF kanye ne-NIH) ngokutholwa okukodwa!

Okusheshayoumphumela:Itholakala emahoreni angu-1.5-2 ngokuhumusha okuzenzakalelayo kwemiphumela okunciphisa ukuqeqeshwa kobuchwepheshe kokusebenza;

Isampula Yokuhlola:isikhwehlela esingu-1-3 mL;

Ukuzwela Okuphezulu:Ukuzwela kokuhlaziya kwamabhaktheriya angu-50/mL kwesifo sofuba kanye ne-2x10³amabhaktheriya/mL amabhaktheriya amelana ne-RIF/INH, okuqinisekisa ukutholwa okuthembekile ngisho noma kunemithwalo ephansi yamabhaktheriya.

I-Target Eningis: I-TB-IS6110; Ukumelana ne-RIF -rpoB (507~503);

Ukumelana ne-INH-InhA/AhpC/katG 315;

Ukuqinisekiswa Kwekhwalithi:Ukulawulwa kweseli kokuqinisekiswa kwekhwalithi yesampula ukunciphisa amaphutha angamanga;

Ukuhambisana Okubanzi: Ukuhambisana nezinhlelo eziningi ze-PCR ezijwayelekile ukuze kufinyeleleke kabanzi elabhorethri;

Ukuthobela Iziqondiso ze-WHO: Ukunamathela eziqondisweni ze-WHO zokuphathwa kwesifo sofuba esingamelana nemithi, ukuqinisekisa ukuthembeka nokufaneleka emikhubeni yezokwelapha.