Esimweni sethu sansuku zonke, igciwane lihlala nathi buthule. Esikhathini esiningi, alibangeli monakalo. Kodwa uma selithole “isikhali” sokumelana nemithi, lingaguquka ngokushesha libe yi-superbug eyingozi.
Kusukela ku-Common Bacterium kuya ku-"Superbug": Ukuqonda i-MRSA
I-Staphylococcus aureusisakazeke kabanzi futhi ivame ukuba yingozi. Usongo lwayo lwangempela lusekuzivumelaniseni kwayo okuphawulekayo. Ngokusebenzisa izinguquko zofuzo noma ukuthola izakhi zofuzo zokumelana, ingaba imelana nama-antibiotic amaningi - okuhlanganisa i-methicillin ne-penicillin - iguquke ibeI-Staphylococcus aureus (MRSA) Engamelani ne-Methicillin.
I-MRSA ingenye yezifo ezivame kakhulu ukumelana namagciwane. Lapho ukumelana namagciwane kukhula, ama-antibiotic amaningi okuqala awasebenzi, okwenza kube nzima kakhulu ukwelapha izifo.
Ngokusho kwedatha ka-2024 eyanyatheliswa ku-I-Lancet, ukufa okubangelwa yi-MRSA kukhuphuke ngaphezu kuka-100% kusukela ngo-1990, kanti cishe ukufa okungu-130,000 kuhlobene ngqo nokutheleleka kwe-MRSA ngo-2021 kuphela.
Izinhlobo Zokutheleleka Kwe-MRSA
I-MRSA ehlobene nokunakekelwa kwempilo (HA-MRSA)kwenzeka ikakhulukazi ezindaweni zezokwelapha njengezibhedlela kanye nezikhungo zokunakekelwa kwesikhathi eside.
I-MRSA ehlobene nomphakathi (CA-MRSA)kuvele ngaphandle kwezindawo zokunakekelwa kwempilo, okuthinte abantu abaphilile ezikoleni, ezindaweni zokuzivocavoca, nakwezinye izindawo zomphakathi.
Ukutheleleka kwe-MRSA kuvame ukuqala njengezinkinga zesikhumba kodwa kungathuthuka ngokushesha kube yizimo ezingathi sína ezithinta igazi, amaphaphu, nezinye izitho zomzimba.
Umthelela Womhlaba Wonke kanye Nabantu Abasengozini
I-MRSA imele ukukhathazeka kwezempilo emhlabeni wonke okunokwehluka okukhulu kuzo zonke izifunda. Izifundo zakamuva zibonisa mayelana namaphethini:
Abasebenzi bezempilo babonisa amazinga aphezulu okuhlala ekoloni
Iziguli ezilaliswe esibhedlela zibhekene nengozi enkulu
Ezinye izifunda zibika amazinga aphezulu kakhulu, kanti ezinye izindawo zibonisa i-MRSA ekuthelelekeni kwe-Staphylococcus aureus okungaphezu kuka-68%
Kungani Kuphuthuma Ukuthola Ngokunembile i-SA kanye ne-MRSA
Ukubhekana nalesi “sitha ngaphakathi,” ukutholakala kusenesikhathi, okusheshayo, nokunembile kubalulekile ekulawuleni ukudluliswa nokusindisa izimpilo.
Izindlela zendabuko ezisekelwe ekwelapheni zidinga amahora angu-48-72 ukuze zikhiqize imiphumela. Phakathi nalokhu kubambezeleka, odokotela bavame ukuthembela kuma-antibiotic e-empirical broad-spectrum — umkhuba ongasheshisa ngokungaqondile ukumelana namagciwane (i-AMR).
Ukuxilongwa kwama-molecule kwanamuhla, ikakhulukazi ubuchwepheshe bokukhulisa ama-multiplex, kunikeza enye indlela esheshayo nethembekile.
Inani Lokutholwa Kwama-Molecular Okusheshayo
Kweziguli: Ukuthola Isikhathi Sokwelashwa Okubucayi
Ukuhlolwa okusheshayo kungaqinisekisa kokubili ukutheleleka kwe-SA kanye nokumelana ne-methicillin kungakapheli amahora. Lokhu kuvumela odokotela ukuthi banikeze ama-antibiotic aqondiwe futhi asebenzayo - bagweme ukwelashwa okungasebenzi kahle futhi bathuthukise imiphumela ngokuphawulekayo.
Kwezibhedlela: Ukuqeda Uchungechunge Lokudlulisela
Ukuhlolwa okusheshayo kuvumela izikhungo zezempilo ukuthi:
Thola ngokushesha abathwali be-MRSA
Sebenzisa izinyathelo zokuzihlukanisa ngesikhathi esifanele
u Vikela abantu abasengozini enkulu (iziguli zase-ICU, izingane ezisanda kuzalwa, abantu asebekhulile)
u Vimbela ukuqubuka kwezifo ezibangelwa yi-nosocomial
Kwezempilo Yomphakathi: Ukuqapha Imikhuba Yokumelana
Ukutholwa okunembile kudala idatha yokumelana ngesikhathi sangempela, okwakha isisekelo sokuqapha kanye nezinqumo zenqubomgomo. Kusebenza njenge "mephu yokumelana" eqondisa ukulawulwa kwe-AMR okunesu.
Kwezenhlalo: Ukuthuthukisa Ukuphathwa Kwama-Antibiotic
Ukuhlukanisa phakathi kwe-SA esengozini kanye ne-MRSA engazweli emithini kusekela ukwelashwa okuqondiswe ngqo kwangempela, kunciphisa ukusetshenziswa okungadingekile kwama-antibiotic e-broad spectrum — okuyisisekelo sokuphathwa kwama-antibiotic ngokwethembeka.
I-Macro kanyeUkuhlolwa Okuncane Okuzenzakalelayo NgokugcweleIsampula-yempenduloIsixazululo Sokuhlola Amamolekyuli se-POCT AIO 800+SA kanye ne-MRSA
Ukuxilongwa kwama-molecule okuthuthukisiwe okufanaI-Macro kanyeIsixazululo Sokuhlola se-POCT AIO 800+ SA & MRSA Esizenzakalelayo Ngokugcweleinikeza ukusebenza kahle kwesampula-kuya-impendulo.
Izinzuzo Eziyinhloko
Ukuhambisana Kwesampula Okuningi
Iyahambisana ne-sputum, ama-nasal swabs, kanye namasampula okutheleleka kwesikhumba/izicubu ezithambile.
Ukuhamba Komsebenzi Okuzenzakalelayo Ngokugcwele
Ukulayisha ngqo kusuka kumashubhu okuqala esampula (1.5 mL–12 mL) kunciphisa isikhathi sokusebenza futhi kunciphisa amaphutha abantu. Kufanelekela izibhedlela, imitholampilo, amalabhorethri, ngisho nezindawo ezilinganiselwe izinsiza.
Ukuzwela Okuphezulu
Ithola umthwalo wamagciwane ongaphansi kuka-1000 CFU/mL kokubili ku-SA kanye ne-MRSA.
Ukuguquka Okusheshayo
Inikeza imiphumela engenzeka emtholampilo zingakapheli amahora.
Amafomethi e-Reagent Amabili
Itholakala ngamafomethi aketshezi nalawo athambile ukuze kunqotshwe izinselele zokugcina nokuthutha.
Ukulawulwa Okuphelele Kokungcola
Uhlelo lokuphepha kwezinto eziphilayo olunezingqimba ezingu-11 oluhlanganisa ukubulala amagciwane kwe-UV, ukuhlunga kwe-HEPA, ukuvala i-parafini, nokuningi.
Ukuhambisana Kwepulatifomu Yomhlaba Wonke
Iyahambisana ne-AIO800 kanye nezinhlelo ze-PCR ezijwayelekile.
Imiphumela Yokunakekelwa Kweziguli Nempilo Yomphakathi
Ukusebenzisa ubuchwepheshe bokuthola obuthuthukisiwe kunikeza izinzuzo ezibalulekile:
Imiphumela Yokwelashwa Ethuthukisiwe: Ukuhlonza kusenesikhathi kuvumela ukukhethwa okufanele kwama-antibiotic, okuholela emiphumeleni engcono yesiguli.
Ukulawulwa Okuthuthukisiwe Kokutheleleka: Ukutholwa okusheshayo kuvumelaizinyathelo zokuzihlukanisa ngokushesha, ukunciphisa ingozi yokudlulisela.
Ukuphathwa Kwama-antibioticUkwelashwa okuqondiwe kusiza ukugcina ukusebenza kahle kwama-antibiotic ngokugwema ukusetshenziswa kwe-broad spectrum okungadingekile.
Amakhono OkuqaphaIzindlela zama-molecule zinikeza idatha ebalulekile yokuqapha amaphethini okumelana nokuhlela impilo yomphakathi.
Ukubhekana nenselele ye-MRSA kudinga indlela ehlelekile ehlanganisa ubuchwepheshe obuthuthukisiwe nemikhuba eyisisekelo yokulawula ukutheleleka.amathuluzi okuxilonga okusheshayo,ukusetshenziswa okufanele kwama-antibiotic,ukuvimbela ukutheleleka okuphumelelayo, futhiukubambisana komhlaba wonkeinikeza indlela yokunciphisa umthelela wokumelana namagciwane.
Ukulungele ukuguqula ukuhlolwa kwe-SA kanye ne-MRSA ngokusebenza kahle kwesampula-kuya-impendulo?
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Isikhathi sokuthunyelwe: Feb-26-2026