Umdlavuza wesine ovame kakhulu kwabesifazane emhlabeni wonke ngokwenani labantu abasha kanye nokufa umdlavuza womlomo wesibeletho ngemva kwebele, i-colorectal namaphaphu. Kunezindlela ezimbili zokugwema umdlavuza womlomo wesibeletho - ukuvimbela okuyinhloko kanye nokuvimbela okwesibili. Ukuvimbela okuyinhloko kuvimbela ama-precancers kwasekuqaleni kusetshenziswa ukugomela i-HPV. Ukuvimbela okwesibili kuthola izilonda ezinomdlavuza ngokuzihlola futhi zelaphe ngaphambi kokuba zibe umdlavuza. Kunezindlela ezintathu ezivame ukwenziwa zokuhlolelwa umdlavuza womlomo wesibeletho, ngayinye yakhelwe uhlobo oluthile lwenhlalo-mnotho okuyi-VIA, i-cytology/Papanicolaou (Pap) smear test kanye nokuhlolwa kwe-HPV DNA. Ngomphakathi jikelele wabesifazane, imihlahlandlela yakamuva ye-WHO yango-2021 manje incoma ukuhlolwa nge-HPV DNA njengokuhlola okuyinhloko okuqala eminyakeni yobudala engama-30 ngezikhawu zeminyaka emihlanu kuya kweyishumi esikhundleni se-Pap Smear noma i-VIA . Ukuhlolwa kwe-HPV DNA kunokuzwela okuphezulu (90 kuya ku-100%) uma kuqhathaniswa ne-pap cytology kanye ne-VIA. Futhi kubiza kakhulu kunezindlela zokuhlola okubukwayo noma i-cytology futhi ifanele zonke izilungiselelo.
Ukuzisampula kungenye indlela ephakanyiswe yi-WHO. ikakhulukazi kwabesifazane abangahlolwanga kahle. Izinzuzo zokuhlola kusetshenziswa ukuzihlolela i-HPV okuziqoqele kuhlanganisa ukwenyuka kokusebenziseka kalula kanye nokwehliswa kwezithiyo zabesifazane. Lapho ukuhlolwa kwe-HPV kutholakala njengengxenye yohlelo lukazwelonke, ukukhetha ukuthi ukwazi ukuzenza isampula kungase kukhuthaze abesifazane ukuthi bafinyelele izinsiza zokuhlola nokwelashwa futhi kuphinde kuthuthukise ukukhava kokuhlolwa.Ukuzisampula ngokwakho kungasiza ukufinyelela okuhlosiwe komhlaba wonke kokumbozwa kokuhlolwa ngo-70% ngo-2030. Abesifazane bangazizwa bekhululeke kakhudlwana ukuthatha amasampula abo, kunokuyobona umsebenzi wezempilo ukuze ahlolelwe umdlavuza womlomo wesibeletho.
