Yini dbumbisaimfivakanye ne-denvvakuthile?
I-Dengue Fever ibangelwa yi-dengue virus (denv), okudluliselwa ngokuyinhloko kubantu ngokulunywa omiyane besifazane abanegciwane, ikakhulukazi i-AEED AGYPTI ne-AEDES ALBOPICCUS.
Kunama-serotypes amane ahlukile we-virus (denv-1, denv-2, denv-3, ne-denv-4). Ukutheleleka nge-serotype eyodwa kunikeza ukungavikeleki kwempilo yonke kuleyo serotype kodwa hhayi kwabanye.
UDengare usakazeka kakhulu ngokulunywa ngumiyane. Izici ezibalulekile zokudluliselwa kwazo zibandakanya:
I-Vector:Le khasiAEDES AEGYPTIUmiyane uchuma ezindaweni zasemadolobheni kanye nezinhlobo zamanzi aqinile.I-AEDES ALOPICTUSfuthi ingadlulisela leli gciwane kepha ayivamile.
Ukudluliswa kwe-Human-to-MomitO:Lapho umiyane eluma umuntu onegciwane, leli gciwane lingena omiyane futhi lingadluliselwa komunye umuntu ngemuva kwenkathi yokufakwa kwezinsuku ezingaba ngu-8-16.
Kungani sinomkhuhlane we-dengue ngisho nasemazweni angewona amakamelo ashisayo?
Ukushintshwa kwesimo sezulu: Ukushisa komhlaba okukhuphukayo kukhula indawo yokuhlala yeUmiyane we-Aedes,Ama-veector aphambili we-dengue.
I-Global Travel and Trade: Ukunyuka okwandayo kwamazwe omhlaba nokuhweba kungaholela ekwethulweni komiyane abaphethe amadenga noma abantu abanegciwane ezindaweni ezingezona ezishisayo.
Ukufuduka kwabantu emabazini: ukufuduka okusheshayo ngaphandle kokuphathwa kwamanzi anele, kwakha izizathu zokuzalela omiyane.
Ukuvumelanisa nomiyane: ama-aedes omiyane, ikakhulukaziAEDES AEGYPTIna-AEDESincwadi yezwi, zivumelana nezimo zezulu ezifudumele kakhulu zezindawo ezinjengezingxenye zaseYurophu naseNyakatho Melika.
Lezi zinto zifaka isandla ngokuhlangene ebukhoneni obukhulayo be-dengue ezindaweni ezingezona ezishisayo.
Ungakuthola kanjani futhi uphathe umkhuhlane we-dengue?
Ukuxilongwa kwemitholampilo kwe-dengue kungakhohlisa ngenxa yezimpawu zayo ezingenangqondo, ezingalingisa ezinye izifo ezibangelwa amagciwane.
Izimpawu:Izimpawu zokuqala zivame ukuvela ezinsukwini ezingama-4- 10 ngemuva kokutheleleka okubandakanya umkhuhlane ophakeme, ubuhlungu bekhanda obukhulu, ubuhlungu be-retro-orbital, ubuhlungu obuhlangene nobunzima, ukuqubuka kanye nokopha kwemisipha. Ezimweni ezinzima, uDengue angathuthukela kuDengue Hemorrhagic Fever (DHF) noma iDengue Short Syndrome (DSS), engaba yingozi empilweni. Ukutholwa kusenesikhathi kusiza ekuphatheni izimpawu ngaphambi kokuba zimbi kakhulu.
UkubonamAma-Ezodes fordbumbisa:
SUkuhlolwa kwe-Erology:Thola ama-antibodies (i-IGM ne-IGG) ngokumelene neDenV, nge-IGM ekhombisa ukutheleleka kwakamuva kanye ne-IGG ephakamisa ukuvezwa kwangaphambilini. Lezi zivivinyo zivame ukusetshenziswaimitholampilona-Ama-Laboratories aphakathi nendawoUkuqinisekisa izifo zamanje noma ezedlule ngesikhathi sokubuyisa noma kubantu abase-asymptomatic ngomlando wokuvezwa.
Ukuhlolwa kwe-NS1 Antigen:Thola i-protein engahlelekile 1 Lezi zivivinyo zivame ukwenziwaIzilungiselelo zokunakekelwa kokunakekelwanjengeimitholampilo, Izibhedlela, futhiIminyango Yezimo EziphuthumayoUkuze uthole ukuthatha izinqumo okusheshayo nokwelashwa.
Ukuhlolwa kwe-NS1 + IGG / IGM:Thola izifo zombili ezisebenzayo nezingesikhathi esedlule ngokuhlolelwa amaprotheni amagciwane kanye nama-antibodies egazini, ukuzenza zilusizo ekuhlukaniseni phakathi kwezifo zakamuva nokuvezwa kwamuva, noma ukukhomba izifo zesibili. Lokhu kuvame ukusetshenziswaIzibhedlela, imitholampilo, futhiAma-Laboratories aphakathi nendawoukuhlolwa okuphelele kokuxilonga.
Ukuhlolwa kwama-molecular:Thola i-viral rna egazini, esebenza kahle kakhulu ngesonto lokuqala lokugula, futhi isetshenziswa ekuqaleni kokutheleleka ngokuqinisekiswa okuqondile, ikakhulukazi emacaleni abucayi. Lezi zivivinyo ziqhutshwa ngokuyinhlokoAma-Laboratories aphakathi nendawongamandla okuxilonga amamolekyuli ngenxa yesidingo semishini ekhethekile.
Ukulandelana:Khomba izinto zofuzo zeDenV ukutadisha izici zalo, ukuhlukahluka, kanye nokuziphendukela kwemvelo, kubalulekile ukucwaninga okuwukuthi, ukuphenya ngokuqubuka, nokulandela ukuguqulwa kwamagciwane namaphethini okuhambisa. Lokhu kuhlola kwenziwa ngaphakathiama-laboratories acwaningana-Ama-labs wezempilo womphakathi akhethekileukuhlaziya okujulile kwe-genomic nezinhloso zokubhekwa.
Njengamanje, akukho ukwelashwa okuqondile kwe-antiviral kwe-dengue. Ukuphathwa kugxile ekunakekelweni kokusekelwa okufana ne-hydration, ukukhululeka kobuhlungu kanye nokuqapha okusondele. Kufanele kuphawulwe ukukhonjwa kokutheleleka kwe-TAHT ngokuzalwa kwe-dengue kungavimbela imiphumela emibi.
IMacro & Micro-Test inikeza amakhithi ahlukahlukene wokuxilonga ama-RDTs, RT-PCR futhi ahlehle kabusha ukuthola ukutholwa kwe-dengue kanye nokuqapha ubhubhane:
Dengue virus I / II / III / IV NUCLEICIkhathi yokutholwa kwe-acid- Uketshezi / Lyophilesed;
I-Dengue NS1 Antigen, Igm / Igg AntibodyKit deal detection kit;
HWTS-FE029-UDengue NS1 Antigen Dection Kit
Izinhlobo ze-Dengue Virus izinhlobo 1/2/3/4 yonke i-genome ukucebisa ikhithi (indlela ye-Multiplex Amplification)
Iphepha elihlobene:
https://www.scieirect.com/Science/Article/Abs/PII/S0168170218300091? Vience3Dub
Isikhathi sePosi: Oct-21-2024