I-Candida Albicans/Candida Tropicalis/Candida Glabrata Nucleic Acid ehlanganisiwe

I-Candida iyisitshalo esikhulu kunazo zonke esivamile se-fungus emzimbeni womuntu. Itholakala kabanzi endleleni yokuphefumula, endleleni yokugaya ukudla, endleleni yokungena korogenital nakwezinye izitho ezixhumana nomhlaba wangaphandle. Ngokuvamile, ayiyona i-pathogenic futhi ingeyamabhaktheriya abangela izifo angena ngengozi. Ngenxa yokusetshenziswa kabanzi kwe-immunosuppressant kanye nenani elikhulu lama-antibiotic e-broad-spectrum, kanye ne-tumor radiotherapy, i-chemotherapy, ukwelashwa okungena ngaphakathi, ukufakelwa kwezitho, i-flora evamile ayilingani futhi ukutheleleka kwe-candida kwenzeka endleleni yokungena korogenital kanye nendlela yokuphefumula. I-Candida albicans ivame kakhulu emtholampilo, futhi kunezinhlobo ezingaphezu kuka-16 zamabhaktheriya abangela izifo angewona ama-Candida albicans, phakathi kwawo i-C. tropicalis, i-C. glabrata, i-C. parapsilosis kanye ne-C. krusei ezivame kakhulu. I-Candida albicans iyisikhunta esibangela izifo esivame ukuhlala endaweni yamathumbu, emlonyeni, esithweni sangasese sowesifazane nakwezinye izitho zomzimba kanye nesikhumba. Lapho ukumelana komzimba kuncipha noma i-microecology iphazamiseka, inganda ngobuningi futhi ibangele izifo. I-Candida tropicalis iyisikhunta esibangela amathuba esitholakala kabanzi emvelweni nasemzimbeni womuntu. Uma ukumelana komzimba kuncipha, i-Candida tropicalis ingabangela izifo zesikhumba, zesitho sangasese sowesifazane, zomgudu womchamo ngisho nezifo zomzimba.

Eminyakeni yamuva nje, phakathi kwezinhlobo ze-Candida ezihlukaniswe neziguli ezine-candidiasis, i-Candida tropicalis ibhekwa njenge-albicans yokuqala noma yesibili engeyona i-Candida (NCAC) ngesilinganiso sokuhlukaniswa, okwenzeka kakhulu ezigulini ezine-leukemia, ukuntuleka kwamasosha omzimba, ukufakwa kwe-catheter isikhathi eside, noma ukwelashwa ngama-antibiotic e-wide-spectrum. Inani labantu abangenwe yi-Candida tropicalis liyahlukahluka kakhulu ngokwezindawo. Inani labantu abangenwe yi-Candida tropicalis liyahlukahluka kakhulu ngokwezindawo. Kwamanye amazwe, ukutheleleka kwe-Candida tropicalis kudlula ngisho ne-Candida albicans. Izici ezibangela izifo zifaka phakathi i-hyphae, i-hydrophobicity ebusweni bamaseli, kanye nokwakheka kwe-biofilm. I-Candida glabrata iyi-fungus evamile ye-pathogenic ye-vulvovaginal candidiasis (VVC). Izinga lokuhlala emakoloni kanye nezinga lokutheleleka kwe-Candida glabrata kuhlobene nobudala babantu. Ukuhlala emakoloni kanye nokutheleleka kwe-Candida glabrata akuvamile kakhulu ezinganeni nasezinganeni, futhi izinga lokuhlala emakoloni kanye nezinga lokutheleleka kwe-Candida glabrata landa kakhulu ngokuguga. Ukusabalala kwe-Candida glabrata kuhlobene nezici ezifana nendawo, ubudala, inani labantu, kanye nokusetshenziswa kwe-fluconazole.