Kungani Igazi Lemilingo Yendle Libalulekile

Umdlavuza we-Coloral Rectum ungenye yezimbangela eziphambili zezifo nokufa okuhlobene nomdlavuza emhlabeni jikelele. Iningi lomdlavuza we-Coloral Rectum likhula kancane kancane kusuka kuma-polyps angaphambi komdlavuza eminyakeni eminingana, okudala ithuba elibalulekile lokutholakala nokungenelela kusenesikhathi.

Esinye sezibonakaliso zokuqala zokuxwayisa yilesiigazi lendle eliyimfihlakalo (FOB)—inani elincane legazi elisendle elingabonakali ngeso lenyama. Ukopha okungabonakali kungabangelwa yizimo ezahlukahlukene zesisu, okuhlanganisa:

• · Ama-adenoma nama-polyps e-Colorectal
• · Umdlavuza we-Colorectal
• · Izilonda zesisu kanye ne-duodenal
• · Isifo samathumbu esivuvukalayo
• · Ezinye izilonda zesisu

Ngenxa yokuthi iziguli eziningi zihlala zingenazo izimpawu ezigabeni zokuqala, ukuthola igazi eliyimfihlakalo sekuyinto ebalulekile ekuhlolweni komdlavuza we-colon osuselwa kubantu.

Umthwalo Womhlaba Wonke Womdlavuza We-Colorectal

Ngokusho kwe-I-International Agency for Research on Cancer (IARC) GLOBOCAN 2022), umdlavuza we-colon uphakathi kwesithathu phakathi kwezinhlobo zomdlavuza ezitholakala kakhulu emhlabeni jikelele futhi uhlala ungowesibili phakathi kwezimbangela ezivame kakhulu zokufa komdlavuza.

Izindaba ezikhuthazayo ukuthi umdlavuza we-colorectal ungavinjelwa kakhulu futhi welapheka uma utholakala kusenesikhathi. Isifo esitholakala endaweni ethile sinesilinganiso sokusinda seminyaka emihlanu esingaphezu kuka-90%, kanti isifo esisakazeke kakhulu sihlotshaniswa nemiphumela emibi kakhulu. Ngakho-ke ukuhlolwa njalo kudlala indima ebalulekile ekunciphiseni ukwanda kwe-CRC kanye nokufa.

I-FIT: Indlela Ekhethwayo Yokuthola Igazi Lemilingo Yendle

Ngokomlando, ukuhlolwa kwegazi elingcolile lendle kwakuncike ezindleleni ezisekelwe ku-guaiac (gFOBT), ezithola umsebenzi we-hemoglobin we-peroxidase. Kodwa-ke, lokhu kuhlolwa kungathinteka yizici zokudla, imithi ethile, kanye ne-hemoglobin engeyona eyomuntu, okuholela emiphumeleni engalungile.

Namuhla,Ukuhlolwa Kwamakhemikhali Endle (FIT)sekuyindlela yokuhlolwa ekhethwayo ezinhlelweni eziningi zokuhlola umdlavuza we-colonectal kuzwelonke.

Uma kuqhathaniswa nokuhlolwa kwamakhemikhali kwendabuko, i-FIT inikeza izinzuzo eziningana ezibalulekile:

• · Ukucaciswa okuphezulungokuthola i-hemoglobin yomuntu ngama-antibodies e-monoclonal
• · Akukho mingcele yokudlangaphambi kokuhlolwa
• · Ukuthobela imithetho kweziguli okuthuthukisiwengenxa yokuqoqwa okulula kwesampula
• · Ukuzwela okukhulu kokuphuma kwegazi okuphansi kwesisu, okwenza kube yimpumelelo enkulu ekuhlolweni komdlavuza we-colonectal

Lezi zinzuzo zisungule i-FITnjengokuhlolwa komugqa wokuqala okungahlaseliindlela emazweni amaningi.

Izincomo Zokuhlola Zamazwe Ngamazwe

Izinhlangano ezinkulu zomhlaba wonke zincoma ukuhlolwa njalo komdlavuza we-colonectal kubantu abadala abasengozini evamile.

• · I-USPSTFincoma ukuhlolwa kwabantu abadala abaneminyaka yobudalaIminyaka engu-45–75, kanye ne-FIT yaminyaka yonke njengenye yamasu okuhlola anconyiwe.
• · I-American Cancer Society (ACS)futhi incoma ukuqala ukuhlolwa okuvamile e-Uneminyaka engu-45 ubudala.
• · Iziqondiso zokuhlola umdlavuza we-colorectal waseYurophuukusekela izinhlelo zokuhlola ezihleliwe ezisekelwe ku-FIT, ngokuvamile njalo eminyakeni emibili kubantu abadala abaneminyaka engu-50-74.

Kungakhathaliseki ukuthi isu lokuhlola liyini, abantu abanemiphumela emihle ye-FIT kufanele bahlolwe i-colonoscopy ukuze kuhlolwe okwengeziwe futhi kuqinisekiswe izilonda ze-colorectal.

Yini Eyenza Ukuhlolwa Kwe-FIT Kwekhwalithi Ephezulu?

Lapho ukhetha ukuhlolwa kwegazi okungabonakali kwendle, ochwepheshe bezempilo kanye nabasebenzisi kufanele bacabangele izici eziningana ezibalulekile:

• · Ukuzwela okuphezulu kokuhlaziya ukuthola amazinga aphansi e-hemoglobin yomuntu
• · Ukucacisa okuphezulu ukunciphisa imiphumela emihle engamanga
• · Iqoqo lamasampula elihlanzekile nelilula
• · Ukusebenza okuzinzile ngesitoreji sokushisa kwegumbi
• · Ukuhamba komsebenzi okulula okusekela kokubili ukusetshenziswa kwasekhaya kanye nezilungiselelo zobungcweti

Ikhithi Yokuhlola Igazi Le-Fecal Occult Fecal Occult Test (i-Colloidal Gold)

I-Macro & Micro-Test ithuthukise i-Ikhithi Yokuhlola Igazi Le-Fecal Occult (i-Colloidal Gold)ngokusekelwe kubuchwepheshe be-immunochromatographic, okuhlinzeka ngesisombululo esisheshayo, esilula, nesihlanzekile sokuhlolwa komdlavuza we-colorectal.

Izici ezibalulekile zifaka:

• · Imiphumela esheshayo yekhwalithi ngemizuzu emi-5-10
• · Ukuzwela kokuhlaziya kwe40 ng/mL i-hemoglobin yomuntu
• · Ubuchwepheshe bokuthola i-immunological, ukunciphisa ukuphazamiseka kokudla kanye nemithi
• · Ishubhu yokusampula ehlanganisiwe entshaukuze kuqoqwe amasampula ahlanzekile futhi ahlanzekile kunemiklamo evamile esekelwe kumakhasethi
• · Ifanele kokubili ukuzihlola kanye nokusetshenziswa kobungcweti
• · Indawo yokugcina izinga lokushisa legumbi (4–30°C) enesikhathi sokuphila seshelufu esingafika ezinyangeni ezingama-24

Idizayinelwe ukuthuthukisa ukufinyeleleka kanye nokuhlangenwe nakho komsebenzisi, ikhithi isekela ukuhlolwa okulula ngenkathi igcina ukusebenza okuthembekile kokuhlaziya.

Ukutholwa kusenesikhathi kusindisa izimpilo. Ngokwenza ukuhlolwa komdlavuza we-colonectal kube lula futhi kufinyeleleke kalula, ukuhlolwa kwe-FIT kungasiza ekuboneni isifo ngaphambi kokuba kuvele izimpawu, okwenza kube lula ukungenelela kwezokwelapha kusenesikhathi kanye nemiphumela engcono yesiguli.

Funda kabanzi mayelana ne-Macro &Ikhithi Yokuhlola Igazi Le-Fecal Occult Yokuhlola Okuncane: