Ucwaningo oluphawulekayo lwakamuva olushicilelwe ku-I-Lancetwembula iqiniso elixakile:Abantu abayizigidi ezingu-1.27 abashonile ngo-2019zazibangelwa ngqo yi-ukumelana namagciwane (i-AMR). Okwethusa nakakhulu,Ama-73% alawa mafa abangelwa yizifo eziyisithupha kuphela.:

1.I-Escherichia coli

2.I-Staphylococcus aureus

3.I-Klebsiella pneumoniae

4.I-Streptococcus pneumoniae

5.I-Acinetobacter baumannii

6.I-Pseudomonas aeruginosa

Phakathi kwazo,I-Klebsiella pneumoniae (KPN), I-Acinetobacter baumannii (Aba), futhiI-Pseudomonas aeruginosa (PA)zivelele njengezimbangela ezinkulu zezifo ezitholakala esibhedlela kanye nokungazweli kwemithi eminingi. Lawa magciwane aya ngokuya emelana nezifoama-carbapenems—umugqa wethu wokugcina wokuzivikela—obeka usongo olukhulu empilweni yomhlaba wonke.

Ukuqonda i-KPN, i-Aba, kanye ne-PA

-I-Klebsiella pneumoniae (KPN)

I-KPN iyigciwane elivame ukutholakala ngengozi futhi iyimbangela ehamba phambili yalokhuisibhedlela esitholiweizifoUma amasosha omzimba omuntu esengozini, angangena ngendlela yokuphefumula, abangele i-pneumonia, izifo zegazi kanye ne-sepsis. Okukhathaza kakhulu yilokhuuhlobo lwe-hvKp ST23 olunamandla kakhulu, evame ukuthwala izakhi zofuzo ze-carbapenem ezifanaI-KPC, i-NDM, i-OXA-48, kanye ne-IMP, okwenza ukwelashwa kube nzima kakhulu.

-I-Acinetobacter baumannii (Aba)

I-Aba iyigciwane elinamandla kakhulu esibhedlela elikwaziyo ukusinda ezindaweni ezikude isikhathi eside. Liyimbangela enkulu yalokhui-pneumonia ehlobene nokuphefumula (i-VAP)kanye nokutheleleka okuhlobene ne-ICU. Ikhono layo eliyingqayizivele lokuthola izakhi zofuzo zokumelana nalo lenze kwaba ngenye yeziyingozi kakhuluizinto eziphilayo ezingamelana nemithi eminingi (i-MDR), lapho ukumelana kwe-carbapenem kudlula khona50% kwezinye izifunda.

-I-Pseudomonas aeruginosa (PA)

I-PA iyigciwane elingabilisi i-Gram-negative elibangelaizifo zokuphefumula eziphansi, ikakhulukazi ezigulini ezinesifo sokuzivikela komzimba esibuthakathaka. Ukuzivumelanisa nezimo kwayo, izinga lokuguquka okusheshayo, kanyeikhono lokwakha i-biofilmkwenza kube nzima ukuqeda izifo.I-PA (CRPA) engamelana ne-Carbapenemkuseyinselele yezokwelapha eqhubekayo emhlabeni wonke.

Indlela Lawa Magciwane Asakazeka Ngayo

Amagciwane e-MDR asakazeka kakhulu ngalezi zindlela ezilandelayo:

-Izindawo zasesibhedlela:imishini engcolile, izindawo, kanye nezandla zabasebenzi bezempilo

-Oxhumana naye ngqo:iziguli ezinegciwane noma abathwali abangenazo izimpawu

-Amaconsi okuphefumula:ikakhulukazi ezinhlotsheni ezihlobene ne-pneumonia

-Izinqubo zokuhlasela:ama-ventilator, ama-catheter, kanye namadivayisi okuhlinza

Izinselele Ekwelapheni

-Ukumelana ne-Carbapenem

Ama-Carbapenems ayacatshangelwaama-antibiotic okugcinaUkuvela kwamagciwane akhiqiza i-carbapenemase kuye kwanciphisa kakhulu ukusebenza kwawo.

-Izinketho Zokwelapha Ezilinganiselwe

-Ama-Polymyxin (isb., i-colistin): ayasebenza kodwa anobuthi obukhulu

-Tigecycline: izinkomba ezilinganiselwe

-Izinto ezintsha (cefiderokol, sulbactam-durlobactam): ziyathembisa kodwa zitholakala kancane

Ukuvimbela kanye nokutholwa kusenesikhathi manje kubaluleke kakhulu kunanini ngaphambili.

Isidingo Sokutholwa Okusheshayo Nokunemba

Lezi zifo ezibangela ukufa okuhlobene ne-AMR emhlabeni wonke, okugqamisa isidingo esiphuthumayo sokuthiukuxilongwa okusheshayo nokuthembekileukuqondisa ukwelashwa okufanele.

Ukutholwa Kwangaphambi Kwesikhathi Kusindisa Ukuphila

Ukuze kuhlangatshezwane nalesi sidingo esiphuthumayo sezokwelapha,Ikhithi Yokuthola I-Macro & Micro-Test's KPN, Aba, PA kanye ne-Drug Resistance Genes Multiplexinikeza ikhambi elinamandla.

Isixazululo esisha,Ikhithi Yokuthola I-Multiplex ye-Macro & Micro-Test, kwenza kube lula ukuhlonza ngesikhathi esisodwaIzakhi zofuzo ze-KPN, Aba, PA, kanye ne-key carbapenemase-I-KPC, I-NDM, I-OXA-48, futhiI-IMP.

Izinzuzo Eziyinhloko:

• Ukutholwa okuqondile okuvela kumasampula e-sputum, ukuqeda izinqubo zokulima ezinde.
• Ukucaca okuphezulu kanye nokuzwela(LoD: 1000 CFU/mL) ukuze uthole imiphumela enembile.
• Isikhathi sokushintsha okusheshayo—kuphumela kuma-35 kuphela-50imizuzu.
• Iyahambisana nezinhlelo ze-PCR ezijwayelekile, ukuqinisekisa ukufinyeleleka okubanzi.

Isicelo Sokwenza Okuthile: Ukuqinisa Ukulwa Nama-Superbugs

OkuthuthukisiweIkhithi Yokuthola I-MultiplexsnguUkuhlolwa Okukhulu Nokuncane inikeza inzuzo ebalulekile ekutholeni amagciwane amelana namagciwane ngokushesha nangokunembile, ivumela ukubhekwa okusheshayo, ukuxilongwa okusheshayo, kanye namasu okwelapha aqondiwe, okugcina kuthuthukisa imiphumela yesiguli kanye nokulawula ukusabalala kokumelana namagciwane.

Joyina impi yokulwa nokumelana namagciwane—hlomisa ilabhorethri yakho ngethuluzi lokuxilonga elisezingeni eliphezulu.

Contact if interested: marketing@mmtest.com