Umdlavuza wamaphaphu usalokhu ungenye yezimbangela eziphambili zokufa okuhlobene nomdlavuza emhlabeni, kanyeumdlavuza wamaphaphu ongewona amangqamuzana amancane (i-NSCLC)kubalwa okungaphezu kwalokho80%kuzo zonke izimo zomdlavuza wamaphaphu. Ngo-2020 kuphela, abantu abangaphezu kuka-Izigidi ezingu-2.2amacala amasha omdlavuza wamaphaphu atholakale emhlabeni jikelele

Njengoba i-precision oncology iqhubeka nokuguqula ukuphathwa kwe-NSCLC,Ukuhlolwa kokuguquka kwezakhi zofuzo kwe-EGFR sekuyinto ebalulekile ekwelapheni ngokunemba.Ukwenza kusebenze izinguquko ku-i-epidermal growth factor receptor (EGFR)Izakhi zofuzo ziphakathi kwezimpawu ze-biomarker ezisebenzayo kakhulu emtholampilo ku-NSCLC, okwenza kube lula ukukhetha izindlela zokwelapha eziqondiwe ezithuthukisa kakhulu imiphumela yezokwelapha ezigulini ezifanelekile.

Uma kuqhathaniswa ne-chemotherapy evamile,Ama-inhibitor e-tyrosine kinase e-EGFR (ama-TKI)ukuvimbela ngokukhetha izindlela zokubonisa ze-EGFR ezingajwayelekile eziqhuba ukukhula nokuqhubeka kwesimila, okunikeza ukusebenza kahle okuthuthukisiwe kanye nephrofayili yokuphepha engcono kakhulu yeziguli ezine-NSCLC eguquliwe yi-EGFR. Ngakho-ke, ukuhlonza okunembile nokufika ngesikhathi kwezinguquko ze-EGFR kubalulekile ekukhetheni ukwelashwa komugqa wokuqala okufanele kakhulu nokusekela izinqumo zokwelapha ezilandelayo njengoba ukumelana kukhula.

Okuvelele Kwesiqondiso

Iziqondiso zemitholampilo zamazwe ngamazwe ezihamba phambili zigcizelela njalo ukubaluleka kokuhlolwa okuphelele kwe-biomarker ezigulini ezine-NSCLC ethuthukile.

Iziqondiso Zokusebenza Kwezokwelapha ze-NCCN ku-Oncology

-Ncoma ukuhlolwa okuphelele kwama-molecule ngaphambi kokuqala ukwelashwa okuqondiswe kumugqa wokuqala ezigulini ezine-NSCLC ethuthukisiwe noma esakazekile.

-Isimo sokuguquka kwe-EGFR sibalulekile ekukhetheni izindlela zokwelapha ezifanele.

I-ESMO Clinical Practice Guideline

Kunconywa ukuhlolwa okuvamile kwe-Ukuguqulwa kwe-EGFR kuma-exons 18-21ukuhlonza iziguli ezifanelekela ukwelashwa okuqondiswe ku-EGFR.

Lezi zincomo zomhlahlandlela ziqokomisa indima ebalulekile yokuhlolwa kokuguquka kwe-EGFR okunembile, okubucayi, nokufika ngesikhathi ekwenzeni ukwelashwa okunembile kweziguli ezine-NSCLC.

Ikhithi Yokuthola Ukuguquka Kwezakhi Zofuzo Ze-EGFR Yomuntu (i-PCR ye-Fluorescence)-Ukutholwa Okunembile Kwezinqumo Zokwelapha Eziqinisekile

Ukuhlolwa kweMacro kanye neMicroIkhithi Yokuthola Ukuguquka Kwezakhi Zofuzo Ze-EGFR Yomuntu (i-PCR ye-Fluorescence)kwenza kube lula ukuthola ngokushesha nangokunembile kwe-Izinguquko ze-EGFR ezingu-29 ezibalulekile emtholampilongaphesheyaama-exons 18–21, ukusekela izinqumo zokwelapha ngokunemba kulo lonke uhambo lwesiguli.

Ukuhlolwa kuthola kokubiliizinguquko ezihambisana nokuzwela izidakamizwa kanye nokumelana nazo, kusiza odokotela ukuhlonza iziguli ezingase zizuze ekwelashweni okuqondiswe ku-EGFR okufanai-gefitinibfuthii-osimertinib, ngenkathi isekela ukwenza izinqumo zokwelapha phakathi nayo yonke inkambo yokwelashwa.

Kungani Kufanele Ukhethe Ikhithi Yokuhlola ye-EGFR ye-Macro kanye ne-Micro-Test?

Ukumbozwa Okuphelele Kokuguquka Kwezakhi Zofuzo

• · UkutholaIzinguquko ze-EGFR ezingu-29 eziphathelene nomtholampilongaphesheya kwe-exons18–21
• · Ihlanganisa kokubiliukuzwela izidakamizwafuthiokuhlobene nokumelanaukuguqulwa kwezakhi zofuzo
• · Ubuchwepheshe be-ARMS obuthuthukisiwenge-patent enhancer ukuze kube nokucaciswa okuthuthukisiwe
• · Ukucebisa nge-Enzymatickunciphisa isizinda se-wild-type futhi kuthuthukisa ukunemba kokutholwa
• · Ubuchwepheshe Bokuvimba Izinga Lokushisakunciphisa ukukhuliswa okungalingani futhi kuthuthukisa ukucaciswa
• · Ithola izinguquko ngeimvamisa ye-allele engu-1% eguquliwe
• · Imiphumela yenhloso zingakapheli imizuzu eyi-120
• · Ukulawula kwangaphakathi kanyei-enzyme ye-UNGnciphisa imiphumela emihle engamanga
• · Isekela kokubiliizicubu, i-plasma noma i-serumama-amples
• · Iyahambisana nezinsimbi ze-PCR zesikhathi sangempela ezivamile
• · Impilo yeshelufu yezinyanga eziyi-12

Ubuchwepheshe Bokuthola Okuthuthukisiwe

Ukusebenza Okuphezulu Kokuhlaziya

Ukuhamba Komsebenzi Okuguquguqukayo

Ukwelapha Okuqondisiwe Ngokuzethemba

Ukuhlolwa kokuguquka kwe-EGFR okuthembekile kuvumela odokotela ukuthi benze izinqumo zokwelapha ezinolwazi kusukela ekuxilongweni kokuqala ngokuqapha ukumelana.

Ukuhlolwa okukodwa. Ukumbozwa okuphelele kokuguquka kwezakhi zofuzo. Ukuzethemba okukhulu ekwenzeni izinqumo zomtholampilo.

Nweba iphothifoliyo yakho ye-Precision Oncology

I-Macro & Micro-Test iphinde inikeze iphothifoliyo ephelele yezixazululo zokuxilonga ama-molecule ze-oncology enembile, okuhlanganisa: i-KRAS, i-BRAF, i-ROS1, i-ALK, i-BCR-ABL, i-TEL-AML nokuningi…

Hlola izixazululo zethu ze-oncology:marketing@mmtest.com