Umqondo wesimila
Isimo siyisitho esisha esakhiwe ukwanda okungajwayelekile kwamaseli emzimbeni, okuvame ukuboniswa njengesisindo sezicubu ezingajwayelekile (inhlama) engxenyeni yendawo yomzimba. Ukwakheka kwe-Tumula kungumphumela wokuphazamiseka okukhulu kokulawulwa kokukhula kwamaseli ngaphansi kwesenzo sezinto ezahlukahlukene zezindlebe. Ukwehlukaniswa okungajwayelekile kwamaseli okuholela ekusungulweni kwesimila kubizwa ngokuthi ukwanda kwe-neoplastic.
Ngo-2019, iseli lomdlavuza lishicilele i-athikili muva nje. Abaphenyi bathola ukuthi i-metformin ingavimbela kakhulu ukukhula kwe-turmus ngesikhathi sokuzila ukudla, futhi kusikisela ukuthi i-PP2A-GSK33-MCL-1 Indlela entsha ingaba yithagethi entsha yokwelashwa kwe-tumor.
Umehluko omkhulu phakathi kwesimila se-bevin nesimila esibi
I-Bevign Tumos, ukukhula kancane, i-capsule, ukukhula kokuvuvukala, ukushelela ukuthinta, ukuhambisa umngcele, akukho membastasis, ngokuvamile izimpawu ezinhle, ngokuvamile akuwona umzimba weziguli.
Isimila esibi (umdlavuza): ukukhula okusheshayo, ukukhula okuhlaselayo, ukunamathela ezindaweni ezizungezile, ukungakwazi ukuhambisa, umkhuhlane olula, ukuvela okulula, ukushesha okulula, ukunciphisa umzimba, I-Anemia nomkhuhlane esiteji sekwephuzile, njll. Uma kungalashwa ngesikhathi, kuvame ukuholela ekufeni.
"Ngoba ama-tum ashubile amugqa kanye nama-tumors amabi awagcini nje ngokuba nokubonakaliswa kwemitholampilo kuphela, kepha okubaluleke kakhulu, i-prognosis yabo yehlukile, ngakho-ke uma usuthole isigaxa emzimbeni wakho nangesikhathi esingenhla, kufanele ufune izeluleko zezokwelashwa ngesikhathi."
Ukwelashwa komuntu ngamunye kwesimila
Iphrojekthi Yohlobo Lomuntu kanye Ne-International Cancer Genome Project
Iphrojekthi Yohlobo Lomuntu, eyasungulwa ngokusemthethweni e-United States ngo-1990, ihlose ukuvula wonke amakhodi ezinhlobo ezingaba ngu-100,000 emzimbeni womuntu bese udweba isibuko sofuzo sabantu.
Ngo-2006, iphrojekthi ye-International Cancer Gene Genome, ngokuhlangene eyethulwe ngamazwe amaningi, kungenye nolunye ucwaningo lwesayensi ngemuva kwephrojekthi yabantu.
Izinkinga ezibalulekile ukwelashwa kwe-tumor
Ukuxilongwa komuntu ngamunye kanye nokwelashwa = Ukuxilongwa komuntu ngamunye + kwezidakamizwa ezihlosiwe
Ezigulini ezahlukahlukene ezihlushwa yisifo esifanayo, indlela yokwelashwa ukusebenzisa umuthi ofanayo kanye nomthamo ojwayelekile, kodwa eqinisweni, iziguli ezahlukahlukene zinokwehluka okukhulu ekuphambukeni kwemithi kanye nokuphendula okunamandla, futhi kwesinye isikhathi lo mehluko ubulale.
Ukwelashwa kwezidakamizwa okuhlosiwe kunezimpawu zokubulawa okukhethiwe kwamaseli we-tumor ngaphandle kokubulala noma kungavamisile ukulimaza amaseli ajwayelekile, kunemiphumela emincane emincane, ethuthukisa kahle ikhwalithi yempilo kanye nokwelashwa kweziguli.
Ngoba ukwelashwa okuhlosiwe kuklanyelwe ukuhlasela ama-molecule athile ahlosiwe, kuyadingeka ukuthola izinhlobo zofuzo zezimila futhi uthole ukuthi iziguli zinezinhloso ezihambelana ngaphambi kokudla izidakamizwa, ukuze zisebenze kanjani umphumela wazo ofanelekayo.
Ukutholwa kwe-Tumor gene
Ukutholwa kwe-Tumor Genene kuyindlela yokuhlaziya nokulandelana kwe-DNA / RNA yamaseli we-tumor.
Ukubaluleka kokutholwa kwe-tumo gene ukuqondisa ukukhethwa kwezidakamizwa kokwelashwa kwezidakamizwa (izidakamizwa ezihlosiwe, ama-infrive pointrevider ama-inhibitors nezinye izinsiza ezintsha, ukwelashwa sekwephuzile), nokuphinda ubikezele.
Izixazululo ezinikezwe yi-ACER Macro & Micro-Test
Uhlobo lomuntu ongumuntu egfr 29 Ikhithi yokutholwa kwe-Mutations (Fluorescence PCRIsihlehlukene
Isetshenziselwa ukutholwa kwezinguquko kokuguqulwa okujwayelekile ku-Exoon 18-21 yeGent Gene Gene ezigulini ezingenamdlavuna ezingezona ezinamaphaphu ezinsimini eVitro.
1. Ukwethulwa kokulawulwa kwekhwalithi yangaphakathi ohlelweni kungaqonda kahle inqubo yokuhlola futhi kuqinisekise ikhwalithi yokuhlola.
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3. Ukucaciswa okuphezulu: Akukho ukusabela kwesiphambano nemiphumela yokutholwa kwe-DNA yohlobo lomuntu wasendle kanye nezinye izinhlobo ze-mutant.
I-Kras 8 Detenion Detection Kit (Fleorescence PCR)
Izinhlobo eziyisishiyagalombili zokuguqulwa kwamakhodi kumakhodi ayi-12 no-13 we-K-RAS gene asetshenziselwe ukutholwa kwe-DNA kukhishwe ezingxenyeni ze-paraffer ezishukunyiswe yi-paraffed.
1. Ukwethulwa kokulawulwa kwekhwalithi yangaphakathi ohlelweni kungaqonda kahle inqubo yokuhlola futhi kuqinisekise ikhwalithi yokuhlola.
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3. Ukucaciswa okuphezulu: Akukho ukusabela kwesiphambano nemiphumela yokutholwa kwe-DNA yohlobo lomuntu wasendle kanye nezinye izinhlobo ze-mutant.
I-Human ROS1 Fusion Gene Mutation Detection Dection Kit (Fluorescence PCR)
Kusetshenziselwa ukuthola kahle izinhlobo eziyi-14 zokuguqulwa kwe-ROS1 Fusion Gene ezigulini ezinomdlavuza we-Human angewona amaphaphu ezinsimini eVitro.
1. Ukwethulwa kokulawulwa kwekhwalithi yangaphakathi ohlelweni kungaqonda kahle inqubo yokuhlola futhi kuqinisekise ikhwalithi yokuhlola.
2. Ukuzwela okuphezulu: amakhophi angama-20 wokuguqulwa kwe-Fusion.
3. Ukucaciswa okuphezulu: Akukho ukusabela kwesiphambano nemiphumela yokutholwa kwe-DNA yohlobo lomuntu wasendle kanye nezinye izinhlobo ze-mutant.
I-Human Eml4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Kusetshenziselwa ukuthola kahle izinhlobo eziyi-12 zokuguqulwa kwe-EML4-ALK Fusion Gene ezigulini ezinomdlavuza we-Human angewona amaphaphu amancane e-Vitro.
1. Ukwethulwa kokulawulwa kwekhwalithi yangaphakathi ohlelweni kungaqonda kahle inqubo yokuhlola futhi kuqinisekise ikhwalithi yokuhlola.
2. Ukuzwela okuphezulu: amakhophi angama-20 wokuguqulwa kwe-Fusion.
3. Ukucaciswa okuphezulu: Akukho ukusabela kwesiphambano nemiphumela yokutholwa kwe-DNA yohlobo lomuntu wasendle kanye nezinye izinhlobo ze-mutant.
I-Human Braf gene v600e dection sokutholwa kwe-Mutation (Fleorescence PCR)
Isetshenziselwa ukuthola kahle ukuguqulwa kwe-bration gene gene v600e kumaparafini ashunyekwe amapharafini amnyama we-melanoma yabantu, umdlavuza we-colorectal, umdlavuza we-thyroid nomdlavuza wamaphaphu eVitro.
1. Ukwethulwa kokulawulwa kwekhwalithi yangaphakathi ohlelweni kungaqonda kahle inqubo yokuhlola futhi kuqinisekise ikhwalithi yokuhlola.
2
3. Ukucaciswa okuphezulu: Akukho ukusabela kwesiphambano nemiphumela yokutholwa kwe-DNA yohlobo lomuntu wasendle kanye nezinye izinhlobo ze-mutant.
Into Cha | Igama lomkhiqizo | Ukucacisa |
I-HWTS-TM006 | I-Human Eml4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | Izivivinyo ezingama-20 / kit Izivivinyo ezingama-50 / kit |
I-HWTS-TM007 | I-Human Braf gene v600e dection sokutholwa kwe-Mutation (Fleorescence PCR) | Izivivinyo ezingama-24 / kit Izivivinyo ezingama-48 / kit |
I-HWTS-TM009 | I-Human ROS1 Fusion Gene Mutation Detection Dection Kit (Fluorescence PCR) | Izivivinyo ezingama-20 / kit Izivivinyo ezingama-50 / kit |
I-HWTS-TM012 | Uhlobo lomuntu ongumuntu egfr 29 Ikhithi yokutholwa kwe-Mutations (Fluorescence PCRIsihlehlukene | 16 izivivinyo / kit 32 izivivinyo / kit |
I-HWTS-TM014 | I-Kras 8 Detenion Detection Kit (Fleorescence PCR) | Izivivinyo ezingama-24 / kit Izivivinyo ezingama-48 / kit |
I-HWTS-TM016 | I-Human Tel-Aml1 Fusion Gene Mutation Detection Dection Kit (Fluorescence PCR) | Izivivinyo ezingama-24 / kit |
I-HWTS-GE010 | I-Human Bcr-Abl Fusion Gene Mutation Dection Dection Dection (Fluorescence PCR) | Izivivinyo ezingama-24 / kit |
Isikhathi sePosi: APR-17-2024