● I-Oncology
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Human PML-RARA Fusion Gene Mutation
Le khithi isetshenziselwa ukutholwa kwekhwalithi yofuzo oluhlanganisiwe lwe-PML-RARA kumasampula omnkantsha womuntu ku-vitro.
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I-TEL-AML1 Fusion Gene Mutation yabantu
Le khithi isetshenziselwa ukutholwa kwekhwalithi yofuzo oluhlanganisiwe lwe-TEL-AML1 kumasampuli womnkantsha womuntu ku-vitro.
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Human BRAF Gene V600E Ukuguqulwa
Le khithi yokuhlola isetshenziselwa ukuthola ngokufanelekile ukuguqulwa kofuzo lwe-BRAF lwe-V600E kumasampula ezicubu ezishunyekiwe zikapharafini zemelanoma yomuntu, umdlavuza we-colorectal, umdlavuza wegilo kanye nomdlavuza wamaphaphu in vitro.
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I-BCR-ABL Fusion Gene Mutation yabantu
Le khithi ifanele ukutholwa kwekhwalithi yama-isoforms we-p190, p210 kanye ne-p230 yofuzo oluhlanganisiwe lwe-BCR-ABL kumasampuli womnkantsha womuntu.
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Ukuguqulwa kwe-KRAS 8
Le khithi ihloselwe ukutholwa kwekhwalithi ye-in vitro yezinguquko ezingu-8 kumakhodoni 12 no-13 ofuzo lwe-K-ras ku-DNA ekhishiwe ezigabeni zomuntu ezishumekwe ngupharafini.
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Ukuguqulwa kwe-EGFR Yomuntu 29
Le khithi isetshenziselwa ukutholwa kwe-in vitro ngendlela efanele ukuguqulwa okujwayelekile kuma-exons 18-21 wofuzo lwe-EGFR kumasampuli asuka ezigulini zomdlavuza wamaphaphu ongewona omncane.
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I-ROS1 Fusion Gene Mutation yabantu
Le kit isetshenziselwa ukutholwa kwekhwalithi ye-in vitro yezinhlobo eziyi-14 zokuguqulwa kofuzo lwe-ROS1 kumasampula omdlavuza wamaphaphu wamangqamuzana angewona amancanyana (Ithebula 1). Imiphumela yokuhlolwa ingeyenkomba yomtholampilo kuphela futhi akufanele isetshenziswe njengesisekelo sodwa sokwelashwa komuntu ngamunye kweziguli.
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I-EML4-ALK Fusion Gene Mutation yomuntu
Le khithi isetshenziselwa ukuthola ngokufanelekile izinhlobo eziyi-12 eziguqukayo zofuzo oluhlanganisiwe lwe-EML4-ALK kumasampula eziguli ezinomdlavuza wamangqamuzana amancane we-in vitro. Imiphumela yokuhlolwa ingeyenkomba yomtholampilo kuphela futhi akufanele isetshenziswe njengesisekelo sodwa sokwelashwa komuntu ngamunye kweziguli. Odokotela kufanele benze izinqumo ezibanzi emiphumeleni yokuhlolwa ngokusekelwe ezicini ezifana nesimo sesiguli, izinkomba zomuthi, ukusabela kokwelashwa, nezinye izinkomba zokuhlola elabhorethri.
