I-Carbapenemase

Incazelo emfushane:

Le khithi isetshenziselwa ukutholwa kwekhwalithi ye-NDM, KPC, OXA-48, IMP ne-VIM carbapenemases ekhiqizwa kumasampula ebhaktheriya atholwe ngemva kwesiko le-in vitro.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Igama lomkhiqizo

HWTS-OT085E/F/G/H -Carbapenemase Detection Kit (Colloidal Gold)

I-Epidemiology

Ama-antibiotic e-Carbapenem angama-atypical β-lactam antibiotics ane-spectrum ebanzi ye-antibacterial kanye nomsebenzi onamandla kakhulu wokulwa namagciwane.[1].Ngenxa yokuqina kwayo ku-β-lactamase kanye nobuthi obuphansi, isibe ngomunye wemithi elwa namagciwane ebaluleke kakhulu ekwelapheni izifo ezinzima zamagciwane.I-Carbapenems izinzile kakhulu ku-plasmid-mediated extended-spectrum β-lactamases (ESBLs), ama-chromosome kanye ne-plasmid-mediated cephalosporinases (ama-AmpC enzymes)[2].

Imingcele Yezobuchwepheshe

Isifunda esiqondiwe I-NDM, KPC, OXA-48, IMP kanye ne-VIM carbapenemases
Izinga lokushisa lesitoreji 4℃-30℃
Uhlobo lwesampula Amasampula egciwane atholwe ngemuva kwesiko
Impilo yeshelufu Izinyanga ezingama-24
Izinsimbi ezisizayo Akudingeki
Izinto Ezisetshenziswayo Ezengeziwe Akudingeki
Isikhathi sokutholwa Amasampula egciwane atholwe ngemuva kwesiko
LoD

Uhlobo lwe-NDM:0.15ng/mL

Uhlobo lwe-KPC: 0.4ng/mL

Uhlobo lwe-OXA-48:0.1ng/mL

Uhlobo lwe-IMP:0.2ng/mL

Uhlobo lwe-VIM:0.3ng/mL.

Umphumela we-hook Ku-NDM, KPC, OXA-48 uhlobo lwe-carbapenemase, awukho umphumela we-hook otholakala kububanzi obungu-100ng/mL;ku-IMP, uhlobo lwe-VIM lwe-carbapenemase, awukho umphumela we-hook otholakala kububanzi obungu-1μg/mL.

Ukugeleza komsebenzi

Ikhithi yokuthola i-Carbapenemase (indlela yegolide ye-Colloidal) -04

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